Prof. Wei-Chuan Shih
Professor
SPIE Involvement:
Conference Program Committee | Editorial Board Member: Journal of Nanophotonics | Author
Area of Expertise:
Nanobiophotonics , Raman/SERS/LSPR , MEMS/NEMS/Fabrication , Plasmonic sensing/actuation , Photothermal applications , Optical Imaging and spectroscopy
Websites:
Profile Summary

Wei-Chuan Shih earned his Ph.D. from MIT Spectroscopy Laboratory/NIH Laser Biomedical Research Center under late laser physicist Dr. Michael S. Feld, studying novel optical spectroscopy techniques for non-invasive chemical/biomedical sensing and disease diagnosis. He also worked extensively on MEMS design and nanofabrication. Prior to joining the U. of Houston, he was Schlumberger research fellow, studying optical analysis of hydrocarbon and offshore oil spill monitoring.
He was MIT Martin Fellow of Sustainability, and won NSF CAREER Award in Biophotonics, inaugural NASA Early CAREER Faculty Award, UH Award for Excellence in Research and Scholarship, UH Cullen College of Engineering Faculty Research Excellence Award, and Cullen College Rising Innovator Award. Dr. Shih has served as Associate Editor of OSA Applied Optics and SPIE Journal of Nanophotonics. He has been elected Senior Member (Inaugural class 2019) of National Academy of Inventors. He is also Senior Member of IEEE, OSA, and SPIE.
Dr. Shih’s primary scientific contribution is in biophotonic chem/biosensing and imaging from various aspects such as optical instrumentation, analytics, micro/nanofabrication and plasmonics. Dr. Shih has published more than 120 articles in the public domain (including 68 peer-reviewed journal papers and 5 invited book chapters). Among the 68 journal articles, 58 were published based on his work at UH, 53 corresponding author, and 50 involved his students. He has 11 issued and 6 pending US patents. As of January 2020, he has an H-index 30 (Google Scholar). Dr. Shih has delivered 60 invited seminar/lectures and 109 conference presentations including invited talks at SPIE Photonics West, SPIE Optics & Photonics, SPIE Defense & Commercial Sensing, OSA Biophotonics Congress, ACS meetings, ECI Advances in Optics, IEEE Photonics Conference, IEEE OMN, IEEE NANOMED, PittCon, SciX/FACSS, META, and etc.
Publications (44)

Proceedings Article | 13 March 2024 Presentation
Proceedings Volume PC12861, PC128610A (2024) https://doi.org/10.1117/12.3005287
KEYWORDS: Biological imaging, Panoramic photography, Nanoparticles, Localized surface plasmon resonances, Plasmonics, Profiling, Plasmonic imaging, Microscopes, Biological research, Viruses

Proceedings Article | 5 October 2023 Presentation
Proceedings Volume PC12654, PC126540Q (2023) https://doi.org/10.1117/12.2678002
KEYWORDS: Biological imaging, Panoramic photography, Nanoparticles, Localized surface plasmon resonances, Spectroscopy, Quantitative analysis, Plasmonic imaging, Molecules, Molecular spectroscopy, Imaging spectroscopy

Proceedings Article | 16 March 2023 Presentation
Proceedings Volume PC12390, PC123900F (2023) https://doi.org/10.1117/12.2655972
KEYWORDS: Panoramic photography, Nanoparticles, Quantitative analysis, Plasmonic imaging, Plasmonics, Surface plasmons, Microscopes, Biological research, Viruses, Pathogens

SPIE Journal Paper | 23 January 2020 Open Access
JBO, Vol. 25, Issue 01, 015004, (January 2020) https://doi.org/10.1117/12.10.1117/1.JBO.25.1.015004
KEYWORDS: Blood, Raman spectroscopy, Iron, Titanium, Statistical analysis, Neptunium, Analytical research, Confocal microscopy, Chemical analysis, Liver

Proceedings Article | 3 June 2019 Paper
Proceedings Volume 11065, 110651L (2019) https://doi.org/10.1117/12.2531109
KEYWORDS: Absorption, Plasmons, Nanostructures, Pathogens, Thermography, Near infrared, Nanoparticles, Gold, Continuous wave operation, Bacteria

Proceedings Article | 7 March 2019 Paper
Proceedings Volume 10863, 1086308 (2019) https://doi.org/10.1117/12.2509392
KEYWORDS: Plasmonics, Bacteria, Gold, Pathogens, Temperature metrology, Glasses, Refractive index, Nanostructures, Raman spectroscopy, Nanoparticles

Proceedings Article | 4 March 2019 Paper
Proceedings Volume 10890, 1089011 (2019) https://doi.org/10.1117/12.2509399
KEYWORDS: Plasmonics, Nanostructures, Gold, Silicon, Glasses, Nanoparticles, Scanning electron microscopy, Nanolithography, Raman scattering, Sensors

Proceedings Article | 4 March 2019 Paper
Proceedings Volume 10932, 1093202 (2019) https://doi.org/10.1117/12.2513619
KEYWORDS: Raman spectroscopy, Spatial light modulators, Hyperspectral imaging, Imaging spectroscopy, Human-computer interaction, Near infrared, Imaging systems, Polymethylmethacrylate, Digital micromirror devices, Raman scattering

Proceedings Article | 26 February 2019 Paper
Proceedings Volume 10869, 108690M (2019) https://doi.org/10.1117/12.2509405
KEYWORDS: Microscopes, Microscopy, Lead, Luminescence, Water, Glasses, Ions, Cameras, Light scattering, Scanning electron microscopy

Proceedings Article | 6 September 2017 Paper
Proceedings Volume 10346, 1034606 (2017) https://doi.org/10.1117/12.2272809
KEYWORDS: Plasmonics, Nanostructures, Biosensing, Surface plasmons, Lithography, Chemistry, Gold, Nanoparticles, Raman scattering, Microscopy

Proceedings Article | 28 April 2017 Presentation
Proceedings Volume 10115, 101150C (2017) https://doi.org/10.1117/12.2253029
KEYWORDS: Nanoparticles, Electron beam lithography, Gold, Nanoplasmonics, Fabrication, Lithography, Nanolithography, Plasmonics, Sensors, Spectroscopy

Proceedings Article | 28 April 2017 Presentation
Proceedings Volume 10115, 101150O (2017) https://doi.org/10.1117/12.2253060
KEYWORDS: Optical fabrication, Optical fibers, Fiber lasers, Laser ablation, Optogenetics, Continuous wave operation, Tissues, Laser optics, Phototherapy, Brain stimulation

Proceedings Article | 24 April 2017 Presentation
Proceedings Volume 10075, 1007504 (2017) https://doi.org/10.1117/12.2253113
KEYWORDS: Gold, Nanoparticles, Microscopy, Plasmonics, Electrons, Spectroscopy, Adsorption, Surface plasmons, Metals, Nanostructures

Proceedings Article | 24 April 2017 Presentation
Proceedings Volume 10072, 100720J (2017) https://doi.org/10.1117/12.2252528
KEYWORDS: Point-of-care devices, Diagnostics, Microscopy, Fabrication, Cameras, Imaging systems, Tissues, Blood, Biomedical optics, Liquids

Proceedings Article | 21 April 2017 Presentation
Proceedings Volume 10080, 1008002 (2017) https://doi.org/10.1117/12.2252989
KEYWORDS: Absorption, Near infrared, Nanoparticles, Gold, Infrared spectroscopy, Absorption spectroscopy, Spectroscopy, Sensors, Plasmonics, Infrared radiation

Proceedings Article | 22 February 2017 Presentation + Paper
Proceedings Volume 10075, 1007505 (2017) https://doi.org/10.1117/12.2253128
KEYWORDS: Nanoparticles, Gold, Molecules, Plasmonics, Surface enhanced Raman spectroscopy, Molecular interactions, Biology, Molecular mechanisms, Biomedical optics, Diagnostics, Microfluidics, Sensors, Charge-coupled devices, Nanoplasmonics

Proceedings Article | 21 February 2017 Presentation + Paper
Jingting Li, Yuankai Yue, Wei-Chuan Shih
Proceedings Volume 10069, 1006914 (2017) https://doi.org/10.1117/12.2253094
KEYWORDS: Raman scattering, Microscopy, Raman spectroscopy, Photons, Scattering, Imaging systems, Laser scattering, Ultrafast lasers, Imaging spectroscopy, Spectroscopes, Digital micromirror devices, Microscopes, Beam shaping, Femtosecond phenomena, Micromirrors, Profiling

Proceedings Article | 20 February 2017 Presentation + Paper
Proceedings Volume 10115, 101150K (2017) https://doi.org/10.1117/12.2253083
KEYWORDS: Plasmonics, Optical lithography, Nanostructures, Gold, Nanoparticles, Nanoplasmonics, Chemistry, Sensors, Spectroscopy, Nanolithography, Scanning electron microscopy, Solids, Spatial light modulators, Refractive index

Proceedings Article | 17 February 2017 Paper
Proceedings Volume 10072, 1007202 (2017) https://doi.org/10.1117/12.2252559
KEYWORDS: Surface enhanced Raman spectroscopy, Molecules, Sensors, Nanostructures, Raman spectroscopy, Nanoparticles, Raman scattering, Gold, Biological and chemical sensing, Chemical elements, Magnesium, Spectroscopy, Agriculture

Proceedings Article | 17 February 2017 Presentation + Paper
Proceedings Volume 10080, 1008006 (2017) https://doi.org/10.1117/12.2253011
KEYWORDS: Gold, Nanoparticles, Nanoplasmonics, Sensors, Plasmonics, Surface plasmons, Spectroscopy, Surface enhanced Raman spectroscopy, Metals, Electrons, Magnesium, Molecules, Raman scattering, Raman spectroscopy

Proceedings Article | 22 April 2016 Paper
Greggy Santos, Felipe Ibañez de Santi Ferrara, Fusheng Zhao, Debora Rodrigues, Wei-Chuan Shih
Proceedings Volume 9724, 97240D (2016) https://doi.org/10.1117/12.2213191
KEYWORDS: Bacteria, Plasmonics, Microorganisms, Nanostructures, Resistance, Pathogens, Gold, Surface plasmons, Resonance enhancement, Raman spectroscopy, Near infrared, Glasses, Scanning electron microscopy, Nanoparticles, In vivo imaging

Proceedings Article | 22 April 2016 Presentation + Paper
Proceedings Volume 9725, 97250F (2016) https://doi.org/10.1117/12.2212318
KEYWORDS: Nanoparticles, Magnesium, Plasmonics, Biosensors, Molecules, Surface enhanced Raman spectroscopy, Gold, Molecular interactions, Luminescence, Raman spectroscopy

Proceedings Article | 21 March 2016 Presentation + Paper
Jingting Li, Ming Li, Greggy Santos, Fusheng Zhao, Wei-Chuan Shih
Proceedings Volume 9705, 97050D (2016) https://doi.org/10.1117/12.2213149
KEYWORDS: Microfluidics, Plasmonics, Metals, Gold, Nanostructures, Liquids, High power lasers, Nanoparticles, Silver, Photothermal effect, Continuous wave operation, Roads, Laser irradiation

Proceedings Article | 7 March 2016 Presentation + Paper
Jingting Li, Ming Li, Yong Du, Greggy Santos, Chandra Mohan, Wei-Chuan Shih
Proceedings Volume 9704, 97040T (2016) https://doi.org/10.1117/12.2212573
KEYWORDS: Spectroscopy, Raman spectroscopy, Kidney, Surface enhanced Raman spectroscopy, Tissues, Microscopes, Point-of-care devices, Microscopy, Diagnostics, Biopsy, Line scan image sensors, Principal component analysis, Mouse models, Gold, Biological research

SPIE Journal Paper | 22 April 2015 Open Access
Yu-Lung Sung, Jenn Jeang, Chia-Hsiung Lee, Wei-Chuan Shih
JBO, Vol. 20, Issue 04, 047005, (April 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.4.047005
KEYWORDS: Lenses, Printing, Inkjet technology, Microscopes, Visibility, Microscopy, Cameras, Biomedical optics, Liquids, Glasses

Proceedings Article | 11 March 2015 Paper
Ming Li, Yong Du, Fusheng Zhao, Jianbo Zeng, Greggy Santos, Chandra Mohan, Wei-Chuan Shih
Proceedings Volume 9340, 934004 (2015) https://doi.org/10.1117/12.2078530
KEYWORDS: Surface enhanced Raman spectroscopy, Kidney, Gold, Molecules, Raman spectroscopy, Point-of-care devices, Urea, Sodium, Raman scattering, Multiplexing

Proceedings Article | 11 March 2015 Paper
Ji Qi, Jianbo Zeng, Fusheng Zhao, Greggy Santos, Steven Hsesheng Lin, Balakrishnan Raja, Ulrich Strych, Richard Willson, Wei-Chuan Shih
Proceedings Volume 9337, 93370D (2015) https://doi.org/10.1117/12.2078552
KEYWORDS: Surface enhanced Raman spectroscopy, Molecules, Gold, Microfluidics, Biomedical optics, Molecular spectroscopy, Diagnostics, Biosensors, Target detection, Silver

Proceedings Article | 11 March 2015 Paper
Fusheng Zhao, Jianbo Zeng, Md Masud Parvez Arnob, Greggy Santos, Wei-Chuan Shih
Proceedings Volume 9340, 93400B (2015) https://doi.org/10.1117/12.2078527
KEYWORDS: Plasmonics, Gold, Nanoparticles, Nanostructures, Thin films, Glasses, Scanning electron microscopy, Surface plasmons, Plasmons, Silicon

Proceedings Article | 9 March 2015 Paper
Ming Li, Fusheng Zhao, Jianbo Zeng, Greggy Santos, Wei-Chuan Shih
Proceedings Volume 9332, 93320E (2015) https://doi.org/10.1117/12.2078534
KEYWORDS: Surface enhanced Raman spectroscopy, Molecules, Raman spectroscopy, Urea, Multiplexing, Molecular spectroscopy, Spectroscopy, Thin films, Gold, Point-of-care devices

Proceedings Article | 5 March 2015 Paper
Greggy Santos, Fusheng Zhao, Jianbo Zeng, Wei-Chuan Shih
Proceedings Volume 9322, 93220J (2015) https://doi.org/10.1117/12.2079214
KEYWORDS: Gold, Light harvesting, Plasmonics, Nanoparticles, Luminescence, Glasses, Molecules, Photothermal effect, Data modeling, Data conversion

Proceedings Article | 5 March 2015 Paper
Ming Li, Fusheng Zhao, Jianbo Zeng, Greggy Santos, Wei-Chuan Shih
Proceedings Volume 9320, 93200K (2015) https://doi.org/10.1117/12.2078519
KEYWORDS: Sensors, Surface enhanced Raman spectroscopy, Microfluidics, Urea, Gold, Raman scattering, Nanostructuring, Raman spectroscopy, Molecules, Point-of-care devices

Proceedings Article | 5 March 2015 Paper
Ji Qi, Narendran Sudheendran, Chih-Hao Liu, Greggy Santos, Eric Young, Alexander Lazar, Dina Lev, Raphael Pollock, Kirill Larin, Wei-Chuan Shih
Proceedings Volume 9318, 931807 (2015) https://doi.org/10.1117/12.2078539
KEYWORDS: Optical coherence tomography, Raman spectroscopy, Tissues, Tissue optics, Tumors, Cancer, Remote sensing, Imaging spectroscopy, Biomedical optics, Laser therapeutics

SPIE Journal Paper | 17 February 2015 Open Access
Wei-Chuan Shih, Kate Bechtel, Mihailo Rebec
JBO, Vol. 20, Issue 05, 051036, (February 2015) https://doi.org/10.1117/12.10.1117/1.JBO.20.5.051036
KEYWORDS: Glucose, Raman spectroscopy, Calibration, Ear, Blood, Error analysis, Statistical analysis, Plasma, Signal to noise ratio, Tissue optics

SPIE Journal Paper | 23 July 2014 Open Access
Ming Li, Fusheng Zhao, Jianbo Zeng, Ji Qi, Jing Lu, Wei-Chuan Shih
JBO, Vol. 19, Issue 11, 111611, (July 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.11.111611
KEYWORDS: Surface enhanced Raman spectroscopy, Sensors, Microfluidics, Gold, Raman scattering, Urea, Molecules, Raman spectroscopy, Nanoparticles, Silver

SPIE Journal Paper | 7 May 2014 Open Access
Ming Li, Jing Lu, Ji Qi, Fusheng Zhao, Jianbo Zeng, Jorn Chi-Chung Yu, Wei-Chuan Shih
JBO, Vol. 19, Issue 05, 050501, (May 2014) https://doi.org/10.1117/12.10.1117/1.JBO.19.5.050501
KEYWORDS: Surface enhanced Raman spectroscopy, Molecules, Molecular spectroscopy, Raman spectroscopy, Urea, Multiplexing, Gold, Forensic science, Thin films, Rhodamine

Proceedings Article | 26 February 2014 Paper
Proceedings Volume 8942, 894208 (2014) https://doi.org/10.1117/12.2038508
KEYWORDS: Optical coherence tomography, Raman spectroscopy, Liver, Kidney, Remote sensing, Tissues, Tissue optics, Tumors, Intestine, Biological research

Proceedings Article | 8 March 2013 Paper
Szu-Te Lin, Mufaddal Gheewala, John Dani, John Wolfe, Wei-Chuan Shih
Proceedings Volume 8565, 85655Y (2013) https://doi.org/10.1117/12.2005707
KEYWORDS: Optical fibers, Brain, Optogenetics, Integrated optics, Capillaries, Waveguides, Silicon, Electrodes, Glasses, Coating

Proceedings Article | 22 February 2013 Paper
Proceedings Volume 8587, 85871N (2013) https://doi.org/10.1117/12.2005718
KEYWORDS: Raman spectroscopy, Imaging spectroscopy, Self-assembled monolayers, Line scan image sensors, Gold, Spatial light modulators, Polymethylmethacrylate, Microscopes, Charge-coupled devices, Optical filters

Proceedings Article | 21 February 2013 Paper
Ji Qi, Pratik Motwani, John Wolfe, Wei-Chuan Shih
Proceedings Volume 8597, 85970I (2013) https://doi.org/10.1117/12.2005727
KEYWORDS: Surface enhanced Raman spectroscopy, Gold, Thin films, Nanostructures, Molecular spectroscopy, Raman scattering, Plasmonics, Etching, Biosensing, Self-assembled monolayers

Proceedings Article | 14 February 2012 Paper
Szu-Te Lin, John Dani, John Wolfe, Wei-Chuan Shih
Proceedings Volume 8251, 82510B (2012) https://doi.org/10.1117/12.908994
KEYWORDS: Capillaries, Brain, Waveguides, Tissues, Silica, Cladding, Optical fibers, Coating, Electrodes, Integrated optics

Proceedings Article | 1 February 2012 Paper
Ji Qi, Pratik Motwani, John Wolfe, Wei-Chuan Shih
Proceedings Volume 8219, 821903 (2012) https://doi.org/10.1117/12.908971
KEYWORDS: Raman spectroscopy, Surface enhanced Raman spectroscopy, Microscopy, Plasmonics, Molecules, Nanostructuring, Microscopes, Polymethylmethacrylate, Line scan image sensors, Molecular spectroscopy

Proceedings Article | 1 May 2009 Paper
W.-C. Shih, A. B. Andrews, Matthew Clayton
Proceedings Volume 7312, 73120V (2009) https://doi.org/10.1117/12.818738
KEYWORDS: Long wavelength infrared, Cameras, Ocean optics, Thin films, Water, Reflection, Optical imaging, Image processing, Raman spectroscopy, Mid-IR

SPIE Journal Paper | 1 November 2007 Open Access
JBO, Vol. 12, Issue 06, 064012, (November 2007) https://doi.org/10.1117/12.10.1117/1.2815692
KEYWORDS: Raman spectroscopy, Statistical analysis, Diagnostics, Arteries, Tissues, Error analysis, Calibration, Spectroscopy, Interference (communication), Biological research

SPIE Journal Paper | 1 May 2005 Open Access
Annika Enejder, Thomas Scecina, Jeankun Oh, Martin Hunter, WeiChuan Shih, Slobodan Sasic, Gary Horowitz, Michael Feld
JBO, Vol. 10, Issue 03, 031114, (May 2005) https://doi.org/10.1117/12.10.1117/1.1920212
KEYWORDS: Glucose, Raman spectroscopy, Calibration, Blood, Skin, Spectroscopy, Tissue optics, In vivo imaging, Statistical analysis, Signal to noise ratio

Showing 5 of 44 publications
Conference Committee Involvement (18)
Plasmonics in Biology and Medicine XXII
26 January 2025 | San Francisco, California, United States
Plasmonics in Biology and Medicine XXI
28 January 2024 | San Francisco, California, United States
Plasmonics in Biology and Medicine XX
29 January 2023 | San Francisco, California, United States
Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2022
21 February 2022 | San Francisco, California, United States
Plasmonics in Biology and Medicine XIX
23 January 2022 | San Francisco, California, United States
Plasmonics in Biology and Medicine XVIII
6 March 2021 | Online Only, California, United States
Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2021
6 March 2021 | Online Only, California, United States
Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2020
3 February 2020 | San Francisco, California, United States
Plasmonics in Biology and Medicine XVII
2 February 2020 | San Francisco, California, United States
Photonic Diagnosis, Monitoring, Prevention, and Treatment of Infections and Inflammatory Diseases 2019
4 February 2019 | San Francisco, California, United States
Plasmonics in Biology and Medicine XVI
3 February 2019 | San Francisco, California, United States
SPIE Translational Biophotonics 2018
14 May 2018 | Houston, Texas, United States
Plasmonics in Biology and Medicine XV
29 January 2018 | San Francisco, California, United States
Plasmonics in Biology and Medicine XIV
30 January 2017 | San Francisco, California, United States
SPIE Translational Biophotonics 2016
16 May 2016 | Houston, Texas, United States
Plasmonics in Biology and Medicine XIII
15 February 2016 | San Francisco, California, United States
Plasmonics in Biology and Medicine XII
7 February 2015 | San Francisco, California, United States
Plasmonics in Biology and Medicine XI
1 February 2014 | San Francisco, California, United States
Showing 5 of 18 Conference Committees
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