On the basis of mathematical modeling, prognostic measures are identified in the individual rehabilitation program (IRP), which influence on the effectiveness of the rehabilitation process and reduce the limitations in disabled individuals with cardiovascular diseases. According to a multivariate stepwise discriminant analysis, the main rehabilitation measures that increase the effectiveness of rehabilitation in persons with disabilities due to cardiovascular diseases are: "restorative therapy", "medical observation", "counseling on physical rehabilitation", "therapeutic physical education", "examination potential professional abilities", "professional orientation", "rational employment" and "adequacy of the profession and specialty recommended in IRP". Taking into account these measures and their implementation will significantly increase the effectiveness of rehabilitation of a person with disabilities with cardiovascular pathology.
On the basis of the created mathematical model prognostically significant measures of medical and social rehabilitation in persons with disabilities with pathology of respiratory organs were determined. The main prognostic significance characteristics of the "effectiveness" of rehabilitation were established and the influence of different types of rehabilitation on the process of recovery and (or) improving livelihoods was estimated. The main rehabilitation measures that increase the effectiveness of rehabilitation in persons with disabilities due to broncho-pulmonary diseases are: "medical observation", "restorative therapy", "spa treatment" and all the measures recommended in the individual rehabilitation program "labor" and "physical rehabilitation", "Examination of potential professional abilities", "vocational training, retraining and advanced training".
The influence of metabolic, molecular genetic- and immune-inflammatory factors on the course of reparative osteogenesis and the formation of bone nonunion of long bones is investigated on the basis of computer statistical analysis and forecasting methods. It has been established that hyperhomocysteinemia, dyslipidemia and cytokine imbalance are negative regressors of the structural and functional state of bone tissue, leading to increased levels of bone resorption markers and the development of systemic and local osteoporosis. The genetic determinants of the course of reparative osteogenesis in a hypoplastic and atrophic type are the homozygous carrier of mutations MTHFR C677T or eNOS T786S, as well as a combination of both polymorphisms.
Based on the information model different variants of osteoplasty, taking into account the persistence, value of critical loading and flexibility of amputation stump below are substantiated. The studies of strength assessment and values of critical load on the stump below knee showed that osteoplastic amputations have obvious advantages as compare d with myoplastic amputations. From the point of view of critical load rather long stumps are inferior to stumps in middle and upper thirds. The character of malleolus bones connection influences the conditions of stump functioning. The most rational are the connections conceptually similar with rigid bony bridge.
The given paper analyzes principles of interaction and analysis of the reflected optical radiation from biotissue
in the process of assessment of regional hemodynamics state in patients with local hypertensive- ischemic pain syndrome
of amputation stumps of lower extremities, applying the method of photoplethysmography.
The purpose is the evaluation of Laser photoplethysmography (LPPG) diagnostic value in examination of
patients with chronic ischemia of lower extremities. Photonic device is developed to determine the level of the peripheral
blood circulation, which determines the basic parameters of peripheral blood circulation and saturation level. Device
consists of two sensors: infrared sensor, which contains the infrared laser radiation source and photodetector, and red
sensor, which contains the red radiation source and photodetector. LPPG method allows to determined pulsatility of
blood flow in different areas of the foot and lower leg, the degree of compensation and conservation perspectives limb.
Surgical treatment of local hypertensive –ischemic pain syndrome of amputation stumps of lower extremities
by means of semiclosed fasciotomy in combination with revasculating osteotrepanation enabled to improve considerably
regional hemodynamics in the tissues of the stump and decrease pain and hypostatic disorders.
In the work the hybrid expert system for stroke diagnosis was presented. The base of expert system consists of neural network and production rules. This program can quickly and accurately set to the patient preliminary and final diagnoses, get examination and treatment plans, print data of patient, analyze statistics data and perform parameterized search for patients.
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