In this work we made an attempt to improve 3D detection of pulmonary nodules on CT images using Conditional GANs extended with Adaptive Instance Normalization and combined Wasserstein Loss for data augmentation (DA). Nodule generating GAN model used for DA was built upon an open-source CT-GAN network which provides high and reproducible results in the nodule generation task. For the evaluation purpose we used DeepSEED model, which is a 3D end-to-end one-stage detector. We tested our approach on the LUNA16 dataset, the subset of LIDC-IDRI. The proposed model outperformed the baseline detection model trained on the original dataset by 3% of average sensitivity. The augmentation helped achieve a remarkable classification rate: 91% of sensitivity and 86% of specificity.
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