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7 March 2023 Disease modeling applications of dynamic full field optical coherence tomography module in retinal studies
Salvatore Azzollini, Tual Monfort, Olivier Thouvenin, Kate F. Grieve
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Proceedings Volume PC12378, Dynamics and Fluctuations in Biomedical Photonics XX; PC1237803 (2023) https://doi.org/10.1117/12.2648331
Event: SPIE BiOS, 2023, San Francisco, California, United States
Abstract
We present the first dynamic full field optical coherence tomography (D-FFOCT) module which can be easily integrated into a commercial microscope. Benefitting from the optical standardization of commercial microscopy, we demonstrate three-dimensional live imaging experiments over time periods of minutes to hours to days thanks to the use of an incubator, able to maintain cell culture conditions. We show timelapse high resolution live images of retinal explants and organoids in disease modeling applications.
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Salvatore Azzollini, Tual Monfort, Olivier Thouvenin, and Kate F. Grieve "Disease modeling applications of dynamic full field optical coherence tomography module in retinal studies", Proc. SPIE PC12378, Dynamics and Fluctuations in Biomedical Photonics XX, PC1237803 (7 March 2023); https://doi.org/10.1117/12.2648331
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KEYWORDS
Optical coherence tomography
3D modeling
Microscopes
3D image processing
Statistical modeling
Light sources
Microscopy
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