Extending Raman's reach: enabling applications via greater sensitivity and speed

David Creasey; Mike Sullivan; Chris Paul; Cicely Rathmell

doi:10.1117/12.2315634

13 February 2018 Extending Raman's reach: enabling applications via greater sensitivity and speed

David Creasey, Mike Sullivan, Chris Paul, Cicely Rathmell

Proceedings Volume 10490, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry; 104900V (2018) https://doi.org/10.1117/12.2315634
Event: SPIE BiOS, 2018, San Francisco, California, United States

Abstract

Over the last decade, miniature fiber optic spectrometers have greatly expanded the ability of Raman spectroscopy to tackle practical applications in the field, from mobile pharmaceutical ID to hazardous material assessment in remote locations. There remains a gap, however, between the typical diode array spectrometer and their more sensitive benchtop analogs. High sensitivity, cooled Raman spectrometers have the potential to narrow that gap by providing greater sensitivity, better SNR, and faster measurement times. In this paper, we'll look at the key factors in the design of high sensitivity miniature Raman spectrometers and their associated accessories, as well as the key metric for direct comparison of these systems - limit of detection. With the availability of our high sensitivity Raman systems operating at wavelengths from the UV to NIR, many applications are now becoming practical in the field, from trace level detection to analysis of complex biological samples.

Citation Download Citation

David Creasey, Mike Sullivan, Chris Paul, and Cicely Rathmell "Extending Raman's reach: enabling applications via greater sensitivity and speed", Proc. SPIE 10490, Biomedical Vibrational Spectroscopy 2018: Advances in Research and Industry, 104900V (13 February 2018); https://doi.org/10.1117/12.2315634

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