Radiation-free quantification of head malformations in craniosynostosis patients from 3D photography

Liyun Tu; Antonio R. Porras; Albert Oh; Natasha Lepore; Manuel Mastromanolis; Deki Tsering; Beatriz Paniagua; Andinet Enquobahrie; Robert Keating; Gary F. Rogers; Marius George Linguraru

doi:10.1117/12.2295374

27 February 2018 Radiation-free quantification of head malformations in craniosynostosis patients from 3D photography

Liyun Tu, Antonio R. Porras, Albert Oh, Natasha Lepore, Manuel Mastromanolis, Deki Tsering, Beatriz Paniagua, Andinet Enquobahrie, Robert Keating, Gary F. Rogers, Marius George Linguraru

Author Affiliations +

Proceedings Volume 10575, Medical Imaging 2018: Computer-Aided Diagnosis; 105751U (2018) https://doi.org/10.1117/12.2295374
Event: SPIE Medical Imaging, 2018, Houston, Texas, United States

Abstract

The evaluation of cranial malformations plays an essential role both in the early diagnosis and in the decision to perform surgical treatment for craniosynostosis. In clinical practice, both cranial shape and suture fusion are evaluated using CT images, which involve the use of harmful radiation on children. Three-dimensional (3D) photography offers noninvasive, radiation-free, and anesthetic-free evaluation of craniofacial morphology. The aim of this study is to develop an automated framework to objectively quantify cranial malformations in patients with craniosynostosis from 3D photography. We propose a new method that automatically extracts the cranial shape by identifying a set of landmarks from a 3D photograph. Specifically, it registers the 3D photograph of a patient to a reference template in which the position of the landmarks is known. Then, the method finds the closest cranial shape to that of the patient from a normative statistical shape multi-atlas built from 3D photographs of healthy cases, and uses it to quantify objectively cranial malformations. We calculated the cranial malformations on 17 craniosynostosis patients and we compared them with the malformations of the normative population used to build the multi-atlas. The average malformations of the craniosynostosis cases were 2.68 ± 0.75 mm, which is significantly higher (p<0.001) than the average malformations of 1.70 ± 0.41 mm obtained from the normative cases. Our approach can support the quantitative assessment of surgical procedures for cranial vault reconstruction without exposing pediatric patients to harmful radiation.

Conference Presentation

Citation Download Citation

Liyun Tu, Antonio R. Porras, Albert Oh, Natasha Lepore, Manuel Mastromanolis, Deki Tsering, Beatriz Paniagua, Andinet Enquobahrie, Robert Keating, Gary F. Rogers, and Marius George Linguraru "Radiation-free quantification of head malformations in craniosynostosis patients from 3D photography", Proc. SPIE 10575, Medical Imaging 2018: Computer-Aided Diagnosis, 105751U (27 February 2018); https://doi.org/10.1117/12.2295374

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available