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Nanoconstructions of gold nanoparticles (NPs) obtained via pulsed laser ablation in liquid with DNA-aptamer specific to protein tumor marker were visualized on the surface of screen-printed electrode using scanning electron microscopy (SEM) and confocal laser scanning microscopy (CLSM). AuNPs/aptamer nanoconstuctions distribution on the solid surface was studied. More uniform coverage of the carbon electrode surface with the nanoconstuctions was showed in comparison with DNA-aptamer alone on the golden electrode surface. Targeted binding of the tumor marker molecules with the AuNPs/DNA-aptamer nanoconstuctions was approved.
Ivan N. Lapin,Anastasiia V. Shabalina,Valery A. Svetlichyi, andOlga S. Kolovskaya
"Visualization of nanoconstructions with DNA-Aptamers for targeted molecules binding on the surface of screen-printed electrodes", Proc. SPIE 10614, International Conference on Atomic and Molecular Pulsed Lasers XIII, 106141R (16 April 2018); https://doi.org/10.1117/12.2304745
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Ivan N. Lapin, Anastasiia V. Shabalina, Valery A. Svetlichyi, Olga S. Kolovskaya, "Visualization of nanoconstructions with DNA-Aptamers for targeted molecules binding on the surface of screen-printed electrodes," Proc. SPIE 10614, International Conference on Atomic and Molecular Pulsed Lasers XIII, 106141R (16 April 2018); https://doi.org/10.1117/12.2304745