Approaches are demonstrated that enable mobile devices, such as smartphones, to function as spectrophotometers with equivalent performance to laboratory instruments for measuring any diagnostic test that generates a colored liquid, fluorescent liquid, or colored solid surface. We envision mobile health diagnostic applications in which smartphone integrated measurement of point-of-care assays enables smart service systems for efficiently connecting patients with health care providers and other health services. A key to this capability is to offer valid tests that are equivalent to those performed in the laboratory by utilizing the same reagents, experimental controls, and calibration standards as conventional assays.
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