An automated preprocessing method based on multiple wavelength measurements for image reconstruction of ultrasound-guided DOT

Murad Althobaiti; Quing Zhu

doi:10.1117/12.2306356

17 May 2018 An automated preprocessing method based on multiple wavelength measurements for image reconstruction of ultrasound-guided DOT

Murad Althobaiti, Quing Zhu

Author Affiliations +

Proceedings Volume 10685, Biophotonics: Photonic Solutions for Better Health Care VI; 1068538 (2018) https://doi.org/10.1117/12.2306356
Event: SPIE Photonics Europe, 2018, Strasbourg, France

Abstract

Ultrasound-guided diffuse optical tomography (DOT) is very favorable and promising imaging technique for the early detection of breast cancer. The technique uses a hand-held probe capable of providing multiple wavelengths measurements in few seconds. These measurements are used to estimate optical proprieties of lesions inside tissue, and calculate the total hemoglobin concentration (tHb). The accurate recovery of breast lesion optical properties requires an effective image reconstruction method. Errors in the measurements caused by low signal-to-noise ratio data and/or movements during data acquisition would reduce the accuracy of reconstructed optical properties. Here is an attempt to preprocess the data based on multiple wavelength measurements for image reconstruction. This approach combines data collected from multiple sets of lesion measurements of different wavelengths to detect and correct outliers in the perturbation. The initial results obtained from the phantom experiments are promising. The approach has enhanced the consistency of the reconstructed images among multiple wavelengths.

Citation Download Citation

Murad Althobaiti and Quing Zhu "An automated preprocessing method based on multiple wavelength measurements for image reconstruction of ultrasound-guided DOT", Proc. SPIE 10685, Biophotonics: Photonic Solutions for Better Health Care VI, 1068538 (17 May 2018); https://doi.org/10.1117/12.2306356

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KEYWORDS

Tissue optics

Breast

Breast cancer

Image restoration

Diffuse optical tomography

Near infrared

Optical properties

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