Development of principles of two-cascaded laser speckle-microscopy with implication to high-precision express diagnostics of chlamydial infection

Onega Ulianova; Yulia Moiseeva; Nadezhda Filonova; Irina Subbotina; Sergey Zaitsev; Yury Saltykov; Tatiana Polyanina; Anna Lyapina; Sergey Ulyanov; Olga Larionova; Sergey Utz; Valentina Feodorova

doi:10.1117/12.2314586

26 April 2018 Development of principles of two-cascaded laser speckle-microscopy with implication to high-precision express diagnostics of chlamydial infection

Onega Ulianova, Yulia Moiseeva, Nadezhda Filonova, Irina Subbotina, Sergey Zaitsev, Yury Saltykov, Tatiana Polyanina, Anna Lyapina, Sergey Ulyanov, Olga Larionova, Sergey Utz, Valentina Feodorova

Author Affiliations +

Proceedings Volume 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX; 107160L (2018) https://doi.org/10.1117/12.2314586
Event: Saratov Fall Meeting 2017, 2017, Saratov, Russian Federation

Abstract

Principles of two-cascaded laser speckle-microscopy prospect for application to express diagnostics of chlamydial infection are developed. Prototype of two-cascaded speckle-microscope is designed and tested. Specific case of illumination of bacterial cells by dynamic speckles is considered. Express method of detection of epithelial cells, containing defects, which are caused by Chlamydia trachomatis bacteria, is suggested. Results of improved recognition of C. trachomatis bacteria are discussed.

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Onega Ulianova, Yulia Moiseeva, Nadezhda Filonova, Irina Subbotina, Sergey Zaitsev, Yury Saltykov, Tatiana Polyanina, Anna Lyapina, Sergey Ulyanov, Olga Larionova, Sergey Utz, and Valentina Feodorova "Development of principles of two-cascaded laser speckle-microscopy with implication to high-precision express diagnostics of chlamydial infection", Proc. SPIE 10716, Saratov Fall Meeting 2017: Optical Technologies in Biophysics and Medicine XIX, 107160L (26 April 2018); https://doi.org/10.1117/12.2314586

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