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18 September 2018 Light-induced extracellular stimulation using organic electrolytic photocapacitors (Conference Presentation)
Eric Glowacki
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Proceedings Volume 10738, Organic and Hybrid Sensors and Bioelectronics XI; 107380V (2018) https://doi.org/10.1117/12.2322613
Event: SPIE Organic Photonics + Electronics, 2018, San Diego, California, United States
Abstract
We report on a nanoscale semiconducting optoelectronic system optimized for neuronal stimulation: the organic electrolytic photocapacitor. The devices comprise a trilayer of metal and p and n semiconductors. When illuminated in physiological solution, these metal-semiconductor devices charge up, transducing light pulses into localized displacement currents that are strong enough to stimulate cells. The devices are freestanding, requiring no wiring or external bias, and are stable in physiological conditions. We have systematically evaluated the ability of photocapacitor devices to alter the cell membrane potential of single nonexcitable cells, generate action potentials in neuronal cell cultures, and stimulate explanted light-insensitive embryonic retinas.
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Eric Glowacki "Light-induced extracellular stimulation using organic electrolytic photocapacitors (Conference Presentation)", Proc. SPIE 10738, Organic and Hybrid Sensors and Bioelectronics XI, 107380V (18 September 2018); https://doi.org/10.1117/12.2322613
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KEYWORDS
Semiconductors
Action potentials
Metals
Optoelectronics
Retina
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