InGaAs detector based Raman spectroscopy for water probing in biological tissue

Shan Yang; Chirantan Sen; Jian-Ge Zhou

doi:10.1117/12.2507573

4 March 2019 InGaAs detector based Raman spectroscopy for water probing in biological tissue

Shan Yang, Chirantan Sen, Jian-Ge Zhou

Proceedings Volume 10888, Biophysics, Biology and Biophotonics IV: the Crossroads; 108880K (2019) https://doi.org/10.1117/12.2507573
Event: SPIE BiOS, 2019, San Francisco, California, United States

Abstract

Water is critical for skin to function normally as a barrier to prevent moisture and heat loss from a body. Raman spectroscopy has high potential in skin hydration analysis as the measurement requires no contacts with the skin. However, traditional CCD based Raman spectrometer has limited performance in detecting high energy vibrations including CH and OH groups. This work reports a customized InGaAs based Raman spectrometer for probing high energy vibration bands. Chicken and pork skin samples were analyzed, and their Raman spectra were compared to other tissues such as fat, tendon, and muscle to determine the spectroscopic identities of CH and OH groups. These results indicate that water components are mostly unbounded in skin tissues. The results further suggest that muscle and tendon components are beneficial for storing water in skin tissue and possibly preventing skin dehydration.

Citation Download Citation

Shan Yang, Chirantan Sen, and Jian-Ge Zhou "InGaAs detector based Raman spectroscopy for water probing in biological tissue", Proc. SPIE 10888, Biophysics, Biology and Biophotonics IV: the Crossroads, 108880K (4 March 2019); https://doi.org/10.1117/12.2507573

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