Diffuse reflectance spectroscopy for Onchocerca Volvulus nodules characterization

Anne Planat-Chrétien; Michel Berger; Belen Pedrique; Samuel Wanji

doi:10.1117/12.2526862

11 July 2019 Diffuse reflectance spectroscopy for Onchocerca Volvulus nodules characterization

Anne Planat-Chrétien, Michel Berger, Belen Pedrique, Samuel Wanji

Proceedings Volume 11074, Diffuse Optical Spectroscopy and Imaging VII; 110741M (2019) https://doi.org/10.1117/12.2526862
Event: European Conferences on Biomedical Optics, 2019, Munich, Germany

Abstract

We show the potential of Diffuse Reflectance Spectroscopy to identify Onchocerca Volvulus nodules, cysts, ganglions and lipomas on humans. We develop a new probe to take into account the geometry of the O. Volvulus model and implement a new measurement protocol and analysis method to deal with the melanin skin contribution. The nodule has a specific intensity and spectral signature compared to its background. It is therefore a relative measure that estimates a signal variation due to the worm and its environment. This may be used to monitor the worm state along time.

Citation Download Citation

Anne Planat-Chrétien, Michel Berger, Belen Pedrique, and Samuel Wanji "Diffuse reflectance spectroscopy for Onchocerca Volvulus nodules characterization", Proc. SPIE 11074, Diffuse Optical Spectroscopy and Imaging VII, 110741M (11 July 2019); https://doi.org/10.1117/12.2526862

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