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9 March 2020 Characterizing the elasticity of thin silk biomaterials using quantitative micro-elastography (Conference Presentation)
Matt Hepburn, Filippo Valente, Phillip Wijesinghe, Rodney J. Dilley, Brendan F. Kennedy
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Proceedings Volume 11242, Optical Elastography and Tissue Biomechanics VII; 1124206 (2020) https://doi.org/10.1117/12.2548513
Event: SPIE BiOS, 2020, San Francisco, California, United States
Abstract
Silk graft biomaterials are proposed to improve the surgical repair of ruptured eardrums. The correct mechanical properties of these silk membranes are critical to ensure optimum patient outcomes. In this study, we use quantitative micro-elastography to characterize the elasticity of three dimensionally printed silk membrane scaffolds. To achieve this, we present a novel sample preparation technique that improves image quality. Using this approach we are able to characterize changes in silk membrane elasticity and study microscale elasticity gradients. We believe this approach will become an important tool to image biomaterials previously thought to be unsuitable for optical elastography.
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Matt Hepburn, Filippo Valente, Phillip Wijesinghe, Rodney J. Dilley, and Brendan F. Kennedy "Characterizing the elasticity of thin silk biomaterials using quantitative micro-elastography (Conference Presentation)", Proc. SPIE 11242, Optical Elastography and Tissue Biomechanics VII, 1124206 (9 March 2020); https://doi.org/10.1117/12.2548513
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KEYWORDS
3D printing
Elastography
Image compression
Image quality
Tissue optics
3D image processing
Coherence (optics)
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