Intracellular Doppler spectroscopy for label-free functional imaging of living tissue (Conference Presentation)

David D. Nolte

doi:10.1117/12.2542443

10 March 2020 Intracellular Doppler spectroscopy for label-free functional imaging of living tissue (Conference Presentation)

David D. Nolte

Author Affiliations +

Proceedings Volume 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020; 1125106 (2020) https://doi.org/10.1117/12.2542443
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

Motions inside living tissues are ubiquitous signatures of the active processes involved in the maintenance of cellular function and health. An innovative label-free non-invasive imaging technology called Biodynamic Imaging (BDI), based on low-coherence interferometry and digital holography, captures intracellular dynamics through ultra-low-frequency Doppler spectra encoding a broad range of cellular and subcellular motions. Clinical trials of BDI assessing patient response to therapy are underway in human ovarian, esophageal and breast cancers.

Conference Presentation

Citation Download Citation

David D. Nolte "Intracellular Doppler spectroscopy for label-free functional imaging of living tissue (Conference Presentation)", Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 1125106 (10 March 2020); https://doi.org/10.1117/12.2542443

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