Label free optical cell and tissue characterization for veterinary pathology and teratology (Conference Presentation)

Jürgen Schnekenburger; Alvaro Barroso Pena; Björn Kemper

doi:10.1117/12.2546737

10 March 2020 Label free optical cell and tissue characterization for veterinary pathology and teratology (Conference Presentation)

Jürgen Schnekenburger, Alvaro Barroso Pena, Björn Kemper

Author Affiliations +

Proceedings Volume 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020; 112510K (2020) https://doi.org/10.1117/12.2546737
Event: SPIE BiOS, 2020, San Francisco, California, United States

Abstract

The pathological examination of regulatory relevant tissue samples is done manually and highly time consuming. Label free optical technologies like quantitative phase microscopy (QPM) and Optical Coherence Tomography (OCT) provide fast analysis of fixated cells and tissues by biophysical parameters. Combination of various wavelengths allows label free QPM tissue characterization equivalent to HE staining. Recent OCT studies showed 3D imaging of rat embryo details as bone structures, full vertebra, whole feet and parts of the skull. The multi-functional potential of QPM and OCT represents a promising new approach for label free phenotyping of regulatory relevant cell and tissue alterations.

Conference Presentation

Citation Download Citation

Jürgen Schnekenburger, Alvaro Barroso Pena, and Björn Kemper "Label free optical cell and tissue characterization for veterinary pathology and teratology (Conference Presentation)", Proc. SPIE 11251, Label-free Biomedical Imaging and Sensing (LBIS) 2020, 112510K (10 March 2020); https://doi.org/10.1117/12.2546737

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available