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Structural connectomics uses tractography for inferring the physical connections between brain regions. An issue of current tractography methods is their large false-positive rate, which makes them not reliable enough for assessing structural connectivity. An approach to deal with this problem is tractogram filtering in which anatomically implausible streamlines are discarded as a post-processing step after tractography. In this talk, I will first review the main approaches and methods that have been proposed in the literature for tractogram filtering and their limitations. Second, I will describe our efforts of using artificial intelligence for improving the accuracy of structural connectivity analyses. Finally, I will give a perspective on the main challenges for the development of new methods in this field in the next few years.
Rodrigo Moreno
"Challenges in tractogram filtering for structural brain connectomics", Proc. SPIE 11469, Emerging Topics in Artificial Intelligence 2020, 114690U (20 August 2020); https://doi.org/10.1117/12.2570548
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Rodrigo Moreno, "Challenges in tractogram filtering for structural brain connectomics," Proc. SPIE 11469, Emerging Topics in Artificial Intelligence 2020, 114690U (20 August 2020); https://doi.org/10.1117/12.2570548