Intra-operative vascular monitoring during balloon angioplasty by vascular wall backscattering light measurement

Emiyu Ogawa; Tsunenori Arai; Hiroshi Kumagai

doi:10.1117/12.2577573

5 March 2021 Intra-operative vascular monitoring during balloon angioplasty by vascular wall backscattering light measurement

Emiyu Ogawa, Tsunenori Arai, Hiroshi Kumagai

Author Affiliations +

Proceedings Volume 11621, Diagnostic and Therapeutic Applications of Light in Cardiology 2021; 116210G (2021) https://doi.org/10.1117/12.2577573
Event: SPIE BiOS, 2021, Online Only

Abstract

We aimed to monitor the state of the vessel wall by irradiating red and near-infrared lasers and measuring the intensity of the backscattered light over time to prevent side effects during balloon angioplasty. In the balloon angioplasty, fiber breakage in the arterial wall causes plastic deformation, which dilates and maintains the lumen of the vessel. However, excessive fiber breakage causes restenosis due to repair reactions of smooth muscle cells and, in the worst case, vessel dissection would occur. Treatment needs to produce fiber breakage in an appropriate range, but there is no way to obtain a vessel fiber breakage situation. Therefore, we are developing a monitoring system that detects the elevated scattering caused by the vascular wall crack that accompanies vascular fiber breakage with laser irradiation from inside the dilating balloon. Exerted healthy porcine carotid arteries were used for dilatation using a device with a plastic diffuse optical fiber inside a 4 mmΦ dilatation balloon. For balloon dilatation, a compressor was used to build a continuous pressurization system that can maintain a maximum expansion pressure of 0.8 MPa. We measured the backscattered light from the vessel wall over time during dilatation.

Conference Presentation

Citation Download Citation

Emiyu Ogawa, Tsunenori Arai, and Hiroshi Kumagai "Intra-operative vascular monitoring during balloon angioplasty by vascular wall backscattering light measurement", Proc. SPIE 11621, Diagnostic and Therapeutic Applications of Light in Cardiology 2021, 116210G (5 March 2021); https://doi.org/10.1117/12.2577573

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