Presentation + Paper
5 March 2021 Multiphoton excitation of Rose Bengal to induce capillary photo-thrombosis
Author Affiliations +
Abstract
In this work, we demonstrate the application of Rose Bengal as a photo-thrombotic agent using 2-photon and 3-photon excitation by measuring the response to multiphotonic excitation. We also demonstrate, in the case of 2-photon excitation, that the mechanism used is different from laser injury alone with a control group of FitC injected mice. Preliminary results show that a capillary photo-thrombosis could be performed up to 200 μm and OCT imaging could confirm blockage.
Conference Presentation
© (2021) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
P. Delafontaine-Martel, Xuecong Lu, Cong Zhang, Rafat Damseh, Frédéric Lesage, and Paul J. Marchand "Multiphoton excitation of Rose Bengal to induce capillary photo-thrombosis", Proc. SPIE 11629, Optical Techniques in Neurosurgery, Neurophotonics, and Optogenetics, 116290G (5 March 2021); https://doi.org/10.1117/12.2577868
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KEYWORDS
Capillaries

Inflammation

Brain

Indocyanine green

Luminescence

Microscopes

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