Quantitative assessment of transmurality of in vivo left atrium radiofrequency ablation lesions by polarization-sensitive optical coherence tomography

Xiaowei Zhao; Ohad Ziv; Walter J. Hoyt; Michael W. Jenkins; Christopher Snyder; Kenneth R. Laurita; Andrew M. Rollins

doi:10.1117/12.2583918

5 March 2021 Quantitative assessment of transmurality of in vivo left atrium radiofrequency ablation lesions by polarization-sensitive optical coherence tomography

Xiaowei Zhao, Ohad Ziv, Walter J. Hoyt, Michael W. Jenkins, Christopher Snyder, Kenneth R. Laurita, Andrew M. Rollins

Author Affiliations +

Proceedings Volume 11630, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV; 116301Y (2021) https://doi.org/10.1117/12.2583918
Event: SPIE BiOS, 2021, Online Only

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Abstract

Pulmonary vein isolation with radiofrequency ablation (RFA) has become the most common procedure to treat Atrial Fibrillation (AF). However, current RFA lesion formation is guided only with indirect information (e.g. temperature, impedance, contact force), which does not guarantee transmural lesions. Non-transmural lesions are understood to contribute to AF recurrence. We have previously demonstrated that polarization-sensitive optical coherence tomography (PSOCT) can monitor RFA lesion transmurality in the left atrium (LA) of living swine. However, it requires expert interpretation. Here, we demonstrate quantitative image quality and lesion transmurality evaluation metrics applied to the in vivo LA RFA PSOCT lesion monitoring data.

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Xiaowei Zhao, Ohad Ziv, Walter J. Hoyt, Michael W. Jenkins, Christopher Snyder, Kenneth R. Laurita, and Andrew M. Rollins "Quantitative assessment of transmurality of in vivo left atrium radiofrequency ablation lesions by polarization-sensitive optical coherence tomography", Proc. SPIE 11630, Optical Coherence Tomography and Coherence Domain Optical Methods in Biomedicine XXV, 116301Y (5 March 2021); https://doi.org/10.1117/12.2583918

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