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Digital holography enables the capture of phase and amplitude from a single camera frame with high sensitivity. Displacements induced by a shear-wave diffuse field are acquired at the surface of a scattering sample. From the acquisitions, the stiffness of the sample can be mapped using a time-reversal-based algorithm. The coupling of digital holography with a time-reversal method achieves full-field quantitative elastography without the need of a controlled or synchronized source of mechanical wave. We present here the validation of the method on tissue-mimicking polymer samples and latest results on ex-vivo and in-vivo biological samples.
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Agathe Marmin, Stefan Catheline, Amir Nahas, "Time-reversal-based passive elastography using full-field digital holography," Proc. SPIE 11645, Optical Elastography and Tissue Biomechanics VIII, 116450D (5 March 2021); https://doi.org/10.1117/12.2578560