Comparison of hepatocellular carcinoma and healthy liver tissues utilizing the optical polarized system

Vi Thao Nguyen; Truc Thanh Nguyen; Hai Thanh Le; Hung Quoc Phan; Hien Thi Thu Pham

doi:10.1117/12.2615713

27 October 2021 Comparison of hepatocellular carcinoma and healthy liver tissues utilizing the optical polarized system

Vi Thao Nguyen, Truc Thanh Nguyen, Hai Thanh Le, Hung Quoc Phan, Hien Thi Thu Pham

Proceedings Volume 11925, Biomedical Imaging and Sensing Conference 2021; 1192512 (2021) https://doi.org/10.1117/12.2615713
Event: SPIE Technologies and Applications of Structured Light, 2021, Online, Japan

Abstract

Liver cancer is currently ranked to be the sixth most common cancer worldwide. Indeed, hepatocellular carcinoma (HCC) is the most frequent type of liver cancer. In this study, we applied an optical polarization system utilizing the Stokes-Mueller matrix to differentiate the HCC tissues with normal ones based on optical characteristics decomposed from the interaction of cancerous and normal tissues with polarized light. Nine optical parameters from tissues were extracted, specifically LB orientation angle (α), the LB phase retardance (β), the CB optical rotation angle (γ), the LD orientation angle (θd), the linear dichroism (D), the circular dichroism (R), the degrees of linear depolarization (e1 and e2), the degree of circular depolarization (e3), and the depolarization index (Δ). The experimental results showed that the orientation angle of linear birefringence (α), linear dichroism (D), and orientation angle of linear dichroism (θd) have the differences between cancerous and normal tissues. It promises a practical penetration to the optical characteristic of liver cancer based on Stokes-Mueller matrix polarimetry.

Citation Download Citation

Vi Thao Nguyen, Truc Thanh Nguyen, Hai Thanh Le, Hung Quoc Phan, and Hien Thi Thu Pham "Comparison of hepatocellular carcinoma and healthy liver tissues utilizing the optical polarized system", Proc. SPIE 11925, Biomedical Imaging and Sensing Conference 2021, 1192512 (27 October 2021); https://doi.org/10.1117/12.2615713

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
11 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Tissues

Liver

Dichroic materials

Tissue optics

Birefringence

Liver cancer

Polarization

Show All Keywords

Keywords/Phrases

Search In:

Publication Years