FreeView: a portable multiphoton imaging system for multimodal high-data-content label-free imaging

Mantas Žurauskas; Matthew Durack; Haohua Tu; Stephen A. Boppart

doi:10.1117/12.2607377

7 March 2022 FreeView: a portable multiphoton imaging system for multimodal high-data-content label-free imaging

Mantas Žurauskas, Matthew Durack, Haohua Tu, Stephen A. Boppart

Proceedings Volume 11949, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX; 1194907 (2022) https://doi.org/10.1117/12.2607377
Event: SPIE BiOS, 2022, San Francisco, California, United States

Abstract

Label-free imaging has re-emerged as a premier approach for imaging living cells and tissues within their natural environment. Label-free imaging provides a non-destructive, high throughput platform for understanding and defining the biophysical states of cells. We anticipate that the real-time spatially-resolved information about the biophysical states of cells will be useful for evaluating and quantifying the changes of these states in response to a variety of external interventions. Here we present a portable high-resolution microscopy system which combines five imaging channels, including four simultaneously excited multiphoton imaging channels (3-photon, 2-photon, third and second harmonic) and wide-field near-infrared imaging.

Conference Presentation

Citation Download Citation

Mantas Žurauskas, Matthew Durack, Haohua Tu, and Stephen A. Boppart "FreeView: a portable multiphoton imaging system for multimodal high-data-content label-free imaging", Proc. SPIE 11949, Advanced Biomedical and Clinical Diagnostic and Surgical Guidance Systems XX, 1194907 (7 March 2022); https://doi.org/10.1117/12.2607377

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