Combined multi-protocols qMRI for thigh muscle analysis: a preliminary study

Mehran Azimbagirad; Guillaume Dardenne; Douraied Ben Salem M.D.; Olivier Remy-Neris; Valerie Burdin

doi:10.1117/12.2604236

10 December 2021 Combined multi-protocols qMRI for thigh muscle analysis: a preliminary study

Mehran Azimbagirad, Guillaume Dardenne, Douraied Ben Salem M.D., Olivier Remy-Neris, Valerie Burdin

Proceedings Volume 12088, 17th International Symposium on Medical Information Processing and Analysis; 120880G (2021) https://doi.org/10.1117/12.2604236
Event: Seventeenth International Symposium on Medical Information Processing and Analysis, 2021, Campinas, Brazil

Abstract

Quantitative MRI (qMRI) has been shown to be crucial for assessing organ dysfunction in the body. Usually, in qMRI approaches, a few metrics are extracted to distinguish normal and abnormal tissues. In this study, we coupled four MRI protocols (mDIXON T1, T1 and T2 mapping and DTI) to obtain 34 complementary metrics including 20 shape metrics, 2 texture metrics and 12 water diffusivity metrics for thigh muscle analysis. These metrics were calculated on both thighs to detect a pathological difference between a pair of right and left muscles. The method is based on a dimension reduction method and a projection of shape and diffusivity metrics into a three-dimensional linear latent space, along with two texture metrics. 5 healthy individuals (10 thighs, each thigh 7 muscles, i.e., 4 flexors and 3 extensors) were scanned to provide the reference scores. The developed pipeline was used to analyse the thighs of 4 patients in order to suggest a specific muscle therapy before total knee arthroplasty (TKA) and for each of the 7 muscles studied. Preliminary results from the analysis of thigh muscle texture, shape and diffusivity showed that this qMRI protocol can help to suggest a targeted, patient-specific exercise plan to improve muscle recovery after TKA surgery. More healthy and pathological subjects are needed to confirm these encouraging results.

Citation Download Citation

Mehran Azimbagirad, Guillaume Dardenne, Douraied Ben Salem M.D., Olivier Remy-Neris, and Valerie Burdin "Combined multi-protocols qMRI for thigh muscle analysis: a preliminary study", Proc. SPIE 12088, 17th International Symposium on Medical Information Processing and Analysis, 120880G (10 December 2021); https://doi.org/10.1117/12.2604236

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available

Members: $17.00

Non-members: $21.00 ADD TO CART

PROCEEDINGS
10 PAGES

DOWNLOAD PAPER SAVE TO MY LIBRARY

GET CITATION

RIGHTS & PERMISSIONS

Get copyright permission Get copyright permission on Copyright Marketplace

KEYWORDS

Diffusion tensor imaging

Magnetic resonance imaging

Principal component analysis

Shape analysis

Surgery

Tissues

Anisotropy

Show All Keywords

Keywords/Phrases

Search In:

Publication Years