High-speed fluorescence microscopy for next-generation life science

Hideharu Mikami

doi:10.1117/12.3008162

20 September 2023 High-speed fluorescence microscopy for next-generation life science

Hideharu Mikami

Proceedings Volume 12608, Biomedical Imaging and Sensing Conference; 126081K (2023) https://doi.org/10.1117/12.3008162
Event: Optics and Photonics International Congress, 2023, Yokohama, Japan

Abstract

Fluorescence microscopy is an essential technique in biomedical research because it can reveal morphological details of complex organisms. Over the past few decades, the spatial resolution of fluorescence microscopy has dramatically improved with super-resolution techniques, contributing significantly to the evolution of life science. On the other hand, temporal resolution (imaging speed) has been overlooked, and its applications have been limited. Therefore, we are developing high-speed fluorescence microscopy techniques to open up new frontiers in life science. Here, we will introduce our recently developed high-speed fluorescence microscopy techniques and their applications to imaging flow cytometry and 3D imaging. We will also discuss the future of high-speed fluorescence imaging that will lead to integrating photonics, informatics, and life science.

Citation Download Citation

Hideharu Mikami "High-speed fluorescence microscopy for next-generation life science", Proc. SPIE 12608, Biomedical Imaging and Sensing Conference, 126081K (20 September 2023); https://doi.org/10.1117/12.3008162

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