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On-chip microscopy is a major improvement toward portable, completely automated, and high-throughput imaging of biological samples. Fabrication of such devices requires the integration of many different components that are not easy to manufacture with standard methods. Femtosecond laser micromachining of transparent materials is a powerful and versatile technology. High resolution, three-dimensional capabilities and rapid-prototyping possibilities make this technology extremely appealing for the combination of optical and fluidic components. Light-sheet microscopy in optofluidic chips will be presented, as well as the use of structured light to achieve super-resolution.
Roberto Osellame
"Integrated advanced microscopy in optofluidic lab-on-a-chip", Proc. SPIE 12622, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI, 126220L (11 August 2023); https://doi.org/10.1117/12.2681475
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Roberto Osellame, "Integrated advanced microscopy in optofluidic lab-on-a-chip," Proc. SPIE 12622, Optical Methods for Inspection, Characterization, and Imaging of Biomaterials VI, 126220L (11 August 2023); https://doi.org/10.1117/12.2681475