Clinical evaluation of tumor promotion by CO2 laser

Robert E. Braun; Charles Liebow

doi:10.1117/12.44001

1 May 1991 Clinical evaluation of tumor promotion by CO₂ laser

Robert E. Braun, Charles Liebow

Proceedings Volume 1424, Lasers in Orthopedic, Dental, and Veterinary Medicine; (1991) https://doi.org/10.1117/12.44001
Event: Optics, Electro-Optics, and Laser Applications in Science and Engineering, 1991, Los Angeles, CA, United States

Abstract

Cancer promotion by CO₂ laser surgery is known to occur in animal models. It is not clear whether these observations are relevant to human disease. To test this, a series of 21 patients with oral lesions treated with CO₂ laser surgery were followed for 2 weeks to 32 months with a mean of 10.2 months. Following laser surgery, 83% of lesions presenting as leukoplakia recurred, whereas no recurrences were observed amongst other lesions. This supports the hypothesis that growth factors released in response to CO₂ laser surgery could promote cancers in patients with initiated lesions.

Citation Download Citation

Robert E. Braun and Charles Liebow "Clinical evaluation of tumor promotion by CO₂ laser", Proc. SPIE 1424, Lasers in Orthopedic, Dental, and Veterinary Medicine, (1 May 1991); https://doi.org/10.1117/12.44001

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