Mathematical model of heat transfer in tissue compared with results from thermography, MRI and laser fluorescence spectroscopy

Juergen Beuthan; Gerhard J. Mueller; Olaf Minet; Hansjoerg Albrecht

doi:10.1117/12.60247

1 August 1992 Mathematical model of heat transfer in tissue compared with results from thermography, MRI and laser fluorescence spectroscopy

Juergen Beuthan, Gerhard J. Mueller, Olaf Minet, Hansjoerg Albrecht

Author Affiliations +

Proceedings Volume 1649, Optical Fibers in Medicine VII; (1992) https://doi.org/10.1117/12.60247
Event: OE/LASE '92, 1992, Los Angeles, CA, United States

Abstract

The use of laser radiation of 1064 nm (Nd:YAG laser) in interstitial laser therapy is coming of age. It is important to realize that the irradiation of tissue contributes to optical changes of the tissue. Consequently, the coefficients of the heat transfer function and the thermodynamic description of the energy balance budget in tissue are not constant. Regarding laser-induced regional hyperthermia non-linear behavior is observed. The heat transfer is estimated to be at multi parameter process. As a first result, a mathematical model is being introduced. The parameters of the model are derived from thermal and spectroscopic in vitro- and in vivo- measurements. Experimental findings of MRI and LIF correspond with the hyperthermal process of the mathematical model.

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Juergen Beuthan, Gerhard J. Mueller, Olaf Minet, and Hansjoerg Albrecht "Mathematical model of heat transfer in tissue compared with results from thermography, MRI and laser fluorescence spectroscopy", Proc. SPIE 1649, Optical Fibers in Medicine VII, (1 August 1992); https://doi.org/10.1117/12.60247

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