Functional image reconstruction enhancement for MR spectroscopic and nuclear medicine images

Ernest M. Stokely; Donald B. Twieg

doi:10.1117/12.59421

1 June 1992 Functional image reconstruction enhancement for MR spectroscopic and nuclear medicine images

Ernest M. Stokely, Donald B. Twieg

Proceedings Volume 1652, Medical Imaging VI: Image Processing; (1992) https://doi.org/10.1117/12.59421
Event: Medical Imaging VI, 1992, Newport Beach, CA, United States

Abstract

Functional images in medicine, such as phosphorus magnetic resonance spectroscopic imaging (SI) images or perfusion studies in nuclear medicine (NM) using 99mTc-HMPAO, are low in resolution compared to x-ray CT or proton MR (anatomic) images. This paper describes an improved, rapid method for enhancing the accuracy and resolution of functional medical images. While both functional and anatomic images are often available for the organ under study, few attempts have been made to use the a priori information in the anatomic images to improve the poor resolution of the corresponding functional images. The proposed technique assumes that compartments can be identified in a high resolution anatomic image of the region under study, and each of these compartments is assumed to contain a spatially heterogeneous concentration of metabolite. The spatial variation of the metabolite is modelled by a series expansion. Application of the method is derived for both MR spectroscopic images, and scintigrams. Noise-free and noisy simulation studies of spectroscopic images are presented which show that the method is robust in the presence of noise, and also when the assumed model is mismatched to the function which describes the actual metabolite compartmental concentration.

Citation Download Citation

Ernest M. Stokely and Donald B. Twieg "Functional image reconstruction enhancement for MR spectroscopic and nuclear medicine images", Proc. SPIE 1652, Medical Imaging VI: Image Processing, (1 June 1992); https://doi.org/10.1117/12.59421

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available