Paper
29 July 1993 Advanced image processing and modeling system for the analysis of cell micrographs in morphology
Qing Wei, Ch. Reme, Peter Stucki
Author Affiliations +
Proceedings Volume 1905, Biomedical Image Processing and Biomedical Visualization; (1993) https://doi.org/10.1117/12.148632
Event: IS&T/SPIE's Symposium on Electronic Imaging: Science and Technology, 1993, San Jose, CA, United States
Abstract
Quantitative analysis of cell-level structures is attracting substantial attention in biomedical studies. This paper presents an advanced digital image processing and modelling system for the automatic analysis of cell micrographs in morphology. For reference, photoreceptors of the rat retina are used. The system implements a new index-based quantitative method developed for the evaluation of light induced lesions in retinal Rod Outer Segments (ROS). The automatic determination of indexes greatly simplifies the description of such damages and permits the statistical analysis of morphological data. A three dimensional synthetic model of retinal ROS was built to interactively simulate the damage mechanisms. The methods reported in this paper are implemented on a graphics super-workstation hardware platform that allows the interactive development of algorithms and procedures through quasi-instant visual feedback.
© (1993) COPYRIGHT Society of Photo-Optical Instrumentation Engineers (SPIE). Downloading of the abstract is permitted for personal use only.
Qing Wei, Ch. Reme, and Peter Stucki "Advanced image processing and modeling system for the analysis of cell micrographs in morphology", Proc. SPIE 1905, Biomedical Image Processing and Biomedical Visualization, (29 July 1993); https://doi.org/10.1117/12.148632
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Cited by 2 scholarly publications.
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KEYWORDS
3D modeling

Image processing

Rods

Photomicroscopy

Retina

Visualization

Algorithm development

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