Kinetics of protein aggregation in biological membranes: a computer simulation study

P. Kvasnichka; Marcela Klevarova

doi:10.1117/12.146149

17 June 1993 Kinetics of protein aggregation in biological membranes: a computer simulation study

P. Kvasnichka, Marcela Klevarova

Proceedings Volume 1921, Laser Spectroscopy of Biomolecules; (1993) https://doi.org/10.1117/12.146149
Event: Laser Spectroscopy of Biomolecules: 4th International Conference on Laser Applications in Life Sciences, 1992, Jyvaskyla, Finland

Abstract

We have studied the kinetics of irreversible diffusion-limited aggregation of particles, randomly walking on a square lattice. Diffusion coefficients of particle aggregates varied with size according to Saffmann-Delbruck equation. For three initial concentrations of particles, we present the time dependences of cluster size and mobility distributions, and of the zeroth and first moments of particle distributions. We show that time variation of the number of clusters can be, to a good approximation, described by a Smoluchowski-type kinetics for the bimolecular reaction A + A yields A in two dimensions.

Citation Download Citation

P. Kvasnichka and Marcela Klevarova "Kinetics of protein aggregation in biological membranes: a computer simulation study", Proc. SPIE 1921, Laser Spectroscopy of Biomolecules, (17 June 1993); https://doi.org/10.1117/12.146149

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