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Medical optical imaging (MOI) and spectroscopy (MOS) use light emitted into opaque tissues in order to determine the interior structure and chemical content. These optical techniques have been developed in an attempt to prospectively identify impending brain injuries before they become irreversible, thus allowing injury to be avoided or minimized. Optical imaging and spectroscopy center around the simple idea that light passes through the body in small amounts, and emerges bearing clues about tissues through which it passed. Images can be reconstructed from such data, and this is the basis of optical tomography. We have used a time-of-flight system reported earlier to monitor oxygenation and image hemorrahage in neonatal brain. This chapter summarizes our early results.
David A. Benaron M.D.,John P. Van Houten,Wai-Fung Cheong,Eben L. Kermit, andRichard A. King
"Early clinical results of time-of-flight optical tomography in a neonatal intensive care unit", Proc. SPIE 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, (30 May 1995); https://doi.org/10.1117/12.209949
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David A. Benaron M.D., John P. Van Houten, Wai-Fung Cheong, Eben L. Kermit, Richard A. King, "Early clinical results of time-of-flight optical tomography in a neonatal intensive care unit," Proc. SPIE 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, (30 May 1995); https://doi.org/10.1117/12.209949