Time-resolved photon migration in a heterogeneous tissue-vessel model

Hanli Liu; Andreas H. Hielscher; Dean C. Kurth M.D.; Steven L. Jacques; Britton Chance

doi:10.1117/12.209961

30 May 1995 Time-resolved photon migration in a heterogeneous tissue-vessel model

Hanli Liu, Andreas H. Hielscher, Dean C. Kurth M.D., Steven L. Jacques, Britton Chance

Proceedings Volume 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation; (1995) https://doi.org/10.1117/12.209961
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

We investigate the relationship between the apparent absorption coefficient and actual absorption coefficient inside the vessels. This analytical formula predicts that the apparent absorption coefficient measured on a biological organ is a volume-weighted sum of the absorption coefficients of different absorbing components. Further, we present some apparent absorption coefficients measured in vivo in animals and humans and show that ignoring the background absorption can lead to significant errors in oxygenation determination.

Citation Download Citation

Hanli Liu, Andreas H. Hielscher, Dean C. Kurth M.D., Steven L. Jacques, and Britton Chance "Time-resolved photon migration in a heterogeneous tissue-vessel model", Proc. SPIE 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue and Model Media: Theory, Human Studies, and Instrumentation, (30 May 1995); https://doi.org/10.1117/12.209961

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