Diode laser systems for photodynamic therapy

William A. Papworth; W. L. Mitchell; Dale D. Severson; Jon A. Warner; Greg B. Rocklin; Greta M. Garbo; Daniel R. Doiron

doi:10.1117/12.208174

1 May 1995 Diode laser systems for photodynamic therapy

William A. Papworth, W. L. Mitchell, Dale D. Severson, Jon A. Warner, Greg B. Rocklin, Greta M. Garbo, Daniel R. Doiron

Proceedings Volume 2392, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IV; (1995) https://doi.org/10.1117/12.208174
Event: Photonics West '95, 1995, San Jose, CA, United States

Abstract

AlGaInP diode lasers generate optical output in a range of the spectrum suitable for the activation of several second=generation photosensitizers including tin ethyl etiopurpurin, SnET2. The development of a system suitable for this application entails coupling the output of multiple highly divergent and astigmatic sources into a single optical fiber for most applications. Various methods of fulfilling this requirement will be discussed along with the advantages and drawbacks of each method. The incorporation into the clinical laser system of on-line dosimetry control of the light delivery parameters will be described along with the results of biological equivalency studies.

Citation Download Citation

William A. Papworth, W. L. Mitchell, Dale D. Severson, Jon A. Warner, Greg B. Rocklin, Greta M. Garbo, and Daniel R. Doiron "Diode laser systems for photodynamic therapy", Proc. SPIE 2392, Optical Methods for Tumor Treatment and Detection: Mechanisms and Techniques in Photodynamic Therapy IV, (1 May 1995); https://doi.org/10.1117/12.208174

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