Interstitial laser photocoagulation of uterine leimyoma

Alastair D. Gordon; Giovanni A. Buonaccorsi; Bipin L. Patel; Jeff J. Broadbent; Wendy Thurrell; Stephen G. Bown

doi:10.1117/12.230311

19 January 1996 Interstitial laser photocoagulation of uterine leimyoma

Alastair D. Gordon, Giovanni A. Buonaccorsi, Bipin L. Patel, Jeff J. Broadbent, Wendy Thurrell, Stephen G. Bown

Proceedings Volume 2623, Medical Applications of Lasers III; (1996) https://doi.org/10.1117/12.230311
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

Uterine leiomyomas (fibroids) are common benign tumors which may cause heavy or painful periods, may present as a pelvic mass and are associated with infertility. Local excision of symptomatic lesions can be difficult and hazardous, and the alternative is hysterectomy. We are investigating interstitial laser photocoagulation (ILP) as a less invasive alternative. Initial experiments were undertaken on 40 fibroids after surgical removal. One or two bare tipped, precharred fibers from a 25 W semiconductor laser (805 nm) were inserted into the center of the fibroid and treatment delivered with 2 - 10 W for 100 - 1000 sec. Specimens were subsequently sectioned perpendicular to the fiber track. Fibroids are very pale and apart from occasional charred tracts there was little evidence of thermal coagulation macroscopically or after haematoxylon and eosin staining. However, using a diaphorase stain technique we were able to demonstrate ellipsoid zones of devitalized tissue up to 20 mm across (15 mm for single fibers). These results suggest that ILP is producing gentle, uniform coagulation which could lead to resorption of treated areas. With appropriate numbers of treatment sites, this could permit minimally invasive management of clinically significant lesions. Clinical studies have commenced treating fibroids with ILP at the time of surgical excision by myomectomy or hysterectomy.

Citation Download Citation

Alastair D. Gordon, Giovanni A. Buonaccorsi, Bipin L. Patel, Jeff J. Broadbent, Wendy Thurrell, and Stephen G. Bown "Interstitial laser photocoagulation of uterine leimyoma", Proc. SPIE 2623, Medical Applications of Lasers III, (19 January 1996); https://doi.org/10.1117/12.230311

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KEYWORDS

Laser coagulation

Surgery

Blood

Fiber lasers

In vitro testing

Semiconductor lasers

Tissues

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