Monitoring of endogenous carbon monoxide dynamics in human breath by tunable diode laser

Eugene V. Stepanov; Mikhail V. Daraselia; Pavel V. Zyrianov; Yurii A. Shulagin; Vladimir A. Skrupskii

doi:10.1117/12.229530

8 January 1996 Monitoring of endogenous carbon monoxide dynamics in human breath by tunable diode laser

Eugene V. Stepanov, Mikhail V. Daraselia, Pavel V. Zyrianov, Yurii A. Shulagin, Vladimir A. Skrupskii

Proceedings Volume 2629, Biomedical Optoelectronics in Clinical Chemistry and Biotechnology; (1996) https://doi.org/10.1117/12.229530
Event: BiOS Europe '95, 1995, Barcelona, Spain

Abstract

High sensitive CO gas analyzer based on tunable diode laser (TDL) was used as a real time monitor of endogenous carbon monoxide in a set of breath physiology experiments. The measurements of the CO content dynamics in exhaled air with 10 ppb sensitivity were attended with detection of carbon dioxide and O₂ in breath, lung ventilation parameters, heart rate and blood analysis using conventional techniques. Temporal variations of endogenous CO in human breath caused by hyperoxia, hypoxia, hyperventilation and sport loading were first studied in real time. Scattering of the CO variation time constants was observed for different tested persons. Possible reasons for this scattering related with the organisms' physiology peculiarities are discussed.

Citation Download Citation

Eugene V. Stepanov, Mikhail V. Daraselia, Pavel V. Zyrianov, Yurii A. Shulagin, and Vladimir A. Skrupskii "Monitoring of endogenous carbon monoxide dynamics in human breath by tunable diode laser", Proc. SPIE 2629, Biomedical Optoelectronics in Clinical Chemistry and Biotechnology, (8 January 1996); https://doi.org/10.1117/12.229530

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