Development of a method to extend, by boron neutron capture process, the therapeutic possibilities of a liver autograft

Tazio Pinelli; Saverio Altieri; F. Fossati; Aris Zonta; U. Prati; L. Roveda; Rosanna Nano

doi:10.1117/12.267875

27 February 1997 Development of a method to extend by boron neutron capture process the therapeutic possibilities of a liver autograft

Tazio Pinelli, Saverio Altieri, F. Fossati, Aris Zonta, U. Prati, L. Roveda, Rosanna Nano

Author Affiliations +

Proceedings Volume 2867, International Conference Neutrons in Research and Industry; (1997) https://doi.org/10.1117/12.267875
Event: Fifth International Conference on Applications of Nuclear Techniques: Neutrons in Research and Industry, 1996, Crete, Greece

Abstract

We present results on surgical technique, neutron filed and irradiation facility concerning the original treatment of the liver diffused metastases. Our method plans to irradiate the isolated organ at a thermal neutron field soon after having been explanted and boron enriched and before being grafted into the same donor. In particular the crucial point of boron uptake was investigated by a rat model with a relevant number of procedure. We give for the first time statistically significant results on the selective boron absorption by tumor tissues.

Citation Download Citation

Tazio Pinelli, Saverio Altieri, F. Fossati, Aris Zonta, U. Prati, L. Roveda, and Rosanna Nano "Development of a method to extend by boron neutron capture process the therapeutic possibilities of a liver autograft", Proc. SPIE 2867, International Conference Neutrons in Research and Industry, (27 February 1997); https://doi.org/10.1117/12.267875

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