Laser-tissue interaction in laser-induced thermotherapy (LITT) of uterine leiomyomas

Roxana Chapman

doi:10.1117/12.275506

16 June 1997 Laser-tissue interaction in laser-induced thermotherapy (LITT) of uterine leiomyomas

Roxana Chapman

Proceedings Volume 2975, Laser-Tissue Interaction VIII; (1997) https://doi.org/10.1117/12.275506
Event: BiOS '97, Part of Photonics West, 1997, San Jose, CA, United States

Abstract

Thirty patients with uterine leiomyomas which were treated by LITT were evaluated histologically, and biologically for oestrogen receptors and epidermal growth factor, at the time of treatment and often subsequently, up to three years later. Three lasers were evaluated: 5W were found to be necessary to produce a lesion 10mm in diameter when the Nd:YAG laser was employed for 500 seconds. The KTP laser alone, using the same number of Joules, produced a larger volume of vaporization and coagulation.However, the most striking effect was achieved with a combination of KTP and YAG. The diode laser alone produced a lesion equivalent to that of the Nd:YAG laser. However, when employed with a fiber splitter and four fibers, each delivering a power of 4W, the volume of necrosis around each fiber was doubled. Finally, the diode laser, when fitted with a diffuser fiber, produced a lesion three times larger than that of the Nd:YAG laser, and there was no char. Histochemical study of oestrogen receptors and immunohistochemical study of epidermal growth factor in the lesions produced by LITT have shown that they are destroyed.

Citation Download Citation

Roxana Chapman "Laser-tissue interaction in laser-induced thermotherapy (LITT) of uterine leiomyomas", Proc. SPIE 2975, Laser-Tissue Interaction VIII, (16 June 1997); https://doi.org/10.1117/12.275506

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available