Development of a red diode laser system for photodynamic therapy

Konstantinos N. Halkiotis; Dido M. Yova; Nikolaos K. Uzunoglou; Georgios Papastergiou; Sotiris Matakias; Ilias Koukouvinos

doi:10.1117/12.316628

14 July 1998 Development of a red diode laser system for photodynamic therapy

Konstantinos N. Halkiotis, Dido M. Yova, Nikolaos K. Uzunoglou, Georgios Papastergiou, Sotiris Matakias, Ilias Koukouvinos

Author Affiliations +

Proceedings Volume 3423, Second GR-I International Conference on New Laser Technologies and Applications; (1998) https://doi.org/10.1117/12.316628
Event: Second GR-I International Conference on New Laser Technologies and Applications, 1997, Olympia, Greece

Abstract

The effectiveness of photodynamic treatment modality has been proven experimentally for a large variety of tumors, during the last years. This therapy utilizes the combined action of light and photosensitizing drug. Until now, a disadvantage of PDT has be the low tissue penetration of light, at the wavelengths of most commonly available lasers, for clinical studies. The red wavelength offers the advantage of increased penetration depth in tissue, in addition several new wavelength offers the advantage of increased penetration depth in tissue, in addition several new photosensitizers present absorption band at the region 630nm to 690nm. The development of high power red diode laser system for photodynamic therapy, has provided a cost effective alternative to existing lasers for use in PDT. This paper will describe the system design, development and performance of a diode laser system, connected with a fiber optic facility, to be used for PDT. The system was based on a high power semiconductor diode laser emitting at 655nm. The laser output power was approximately 60mW at the output of a 62.5/125/900 micron fiber optic probe. FUll technical details and optical performance characteristics of the system will be discussed in this paper.

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Konstantinos N. Halkiotis, Dido M. Yova, Nikolaos K. Uzunoglou, Georgios Papastergiou, Sotiris Matakias, and Ilias Koukouvinos "Development of a red diode laser system for photodynamic therapy", Proc. SPIE 3423, Second GR-I International Conference on New Laser Technologies and Applications, (14 July 1998); https://doi.org/10.1117/12.316628

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