Initiation of apoptosis by photosensitization with hypocrellin A and the repression of Vitamin E

En-Hua Cao; Jian Zhang; Jingfu Li

doi:10.1117/12.317884

7 August 1998 Initiation of apoptosis by photosensitization with hypocrellin A and the repression of Vitamin E

En-Hua Cao, Jian Zhang, Jingfu Li

Proceedings Volume 3548, Biomedical Optics and Lasers: Diagnostics and Treatment; (1998) https://doi.org/10.1117/12.317884
Event: Photonics China '98, 1998, Beijing, China

Abstract

PDT-induced HeLa cells apoptosis was evidenced by morphological changes, DNA fragmentation and decrease of mitochondria dehydrogenase activity. Apoptosis was associated with the formation of IP₃ of photosensitized cells and rapid release of Ca²⁺ from intracellular pools. Vitamin E, which was added before irradiation, could significantly protect cells against cell death, indicating that reactive oxygen species (ROS) play an important role in apoptotic cell death.

Citation Download Citation

En-Hua Cao, Jian Zhang, and Jingfu Li "Initiation of apoptosis by photosensitization with hypocrellin A and the repression of Vitamin E", Proc. SPIE 3548, Biomedical Optics and Lasers: Diagnostics and Treatment, (7 August 1998); https://doi.org/10.1117/12.317884

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available