Results on the human sclera and skin optical properties controlled by employing administration of various chemical agents are presented. CW transmittance and reflectance measurements as well as intensity correlation experiments were used for tissue structural and optical properties monitoring. As chemical applicators--controllers osmotically active solutions, such as trazograph, glucose, polyethylene glycol, propylene glycol, glycerol, as well as aprotonic solutions like dimethyl sulphoxide were used. The characteristic time response of the human sclera optical clearing lying in the range 3 - 10 min was defined. The diffusion coefficients describing the samples of the human sclera permeability to various solutes were experimentally estimated. Presented results are general and can be applicable for description of many other fibrous tissues.
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