X-ray phase-contrast imaging study of soft tissue and bone samples

Dachao Gao; Andrew Pogany; Andrew Wesley Stevenson; Timur E. Gureyev; Stephen W. Wilkins

doi:10.1117/12.349509

28 May 1999 X-ray phase-contrast imaging study of soft tissue and bone samples

Dachao Gao, Andrew Pogany, Andrew Wesley Stevenson, Timur E. Gureyev, Stephen W. Wilkins

Proceedings Volume 3659, Medical Imaging 1999: Physics of Medical Imaging; (1999) https://doi.org/10.1117/12.349509
Event: Medical Imaging '99, 1999, San Diego, CA, United States

Abstract

Conventional radiography is based on absorption contrast and geometrical (ray) optics. After an outline of the relevant theory, this article reports results displaying both phase- and absorption-contrast, collected with a technique which utilizes a micro-focus x-ray source to achieve a high degree of spatial coherence, and relatively large object-to-image distances to enable (wave) interference effects (Fresnel diffraction) to occur and manifest themselves as phase contrast in the image plane. Both soft tissue (chicken knee) and hard tissue (finger bone) samples are investigated for a range of source sizes and object-to-image distances, encompassing conditions somewhat analogous to conventional radiography. Variation in image contrast and resolution as a function of these variables is observed and discussed.

Citation Download Citation

Dachao Gao, Andrew Pogany, Andrew Wesley Stevenson, Timur E. Gureyev, and Stephen W. Wilkins "X-ray phase-contrast imaging study of soft tissue and bone samples", Proc. SPIE 3659, Medical Imaging 1999: Physics of Medical Imaging, (28 May 1999); https://doi.org/10.1117/12.349509

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