Stephane R. Chamot,1 Benno L. Petrig,1 Constantin J. Pournaras,2 Christine L. Percicot,3 George N. Lambrou,3 Charles E. Riva4
1Institut de Recherche en Ophtalmologie (Switzerland) 2Univ. Eye Clinic (Switzerland) 3Novartis Ophthalmics Research (Switzerland) 4Institut de Recherche en Ophtalmologie and Univ. of Lausanne (Switzerland)
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The technique of phosphorescence quenching by O2 (PQ) allows the non-invasive measurement of the partial pressure of oxygen in blood (pO2blood). This technique and its application to the investigation of the pO2blood in the microvasculature of the retina and optic nerve head (ONH) of two animal species is described. Using the imaging mode of PQ, 2-dimensional pO2blood maps were obtained to investigate the response of the pO2blood to various physiological stimuli in miniature pigs and the effect of experimental glaucoma in monkeys. Applied in its focal mode, PQ allows measurements of the pO2blood with a time resolution of 1 second and is adequate to investigate the pO2blood time course during light stimulation.
Stephane R. Chamot,Benno L. Petrig,Constantin J. Pournaras,Christine L. Percicot,George N. Lambrou, andCharles E. Riva
"Application of phosphorescence quenching by O2 to the investigation of O2 delivery to ocular tissues", Proc. SPIE 4433, Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy, (26 October 2001); https://doi.org/10.1117/12.446498
ACCESS THE FULL ARTICLE
INSTITUTIONAL Select your institution to access the SPIE Digital Library.
PERSONAL Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.
The alert did not successfully save. Please try again later.
Stephane R. Chamot, Benno L. Petrig, Constantin J. Pournaras, Christine L. Percicot, George N. Lambrou, Charles E. Riva, "Application of phosphorescence quenching by O2 to the investigation of O2 delivery to ocular tissues," Proc. SPIE 4433, Laser-Tissue Interactions, Therapeutic Applications, and Photodynamic Therapy, (26 October 2001); https://doi.org/10.1117/12.446498