Diffraction-limited 3D cell volume derivation for scattering data analysis

Navalgund A. H. K. Rao; Monica Barbu-McInnis; Maria Helguera; Charles J. Daly

doi:10.1117/12.462170

11 April 2002 Diffraction-limited 3D cell volume derivation for scattering data analysis

Navalgund A. H. K. Rao, Monica Barbu-McInnis, Maria Helguera, Charles J. Daly

Proceedings Volume 4687, Medical Imaging 2002: Ultrasonic Imaging and Signal Processing; (2002) https://doi.org/10.1117/12.462170
Event: Medical Imaging 2002, 2002, San Diego, California, United States

Abstract

Ultrasound speckle carries information about the interrogated scattering microstructure. The complex signal is represented as a superposition of signals due to all scatterers within a resolution cell volume, V_E. A crossbeam geometry with separate transmit and receive transducers is well suited for such studies. The crossbeam volume, V_E is defined in terms of the overlapping diffraction beam patterns. Given the focused piston transducer's radius and focal distance, a Lommel diffraction formulation suitable for monochromatic excitation is used to calculate V_E as a function of frequency and angle. This formulation amounts to a Fresnel approximation to the diffraction problem and is not limited to the focal zone or the far field. Such diffraction corrections as V_E are needed to remove the system effects when trying to characterize material using moment analysis. Theoretically, V_E is numerically integrated within the overlapping region of the product of the transmit-receive transfer functions. Experimentally, V_E was calculated from the field pattern of a medium-focused transducer excited by a monochromatic signal detected by a 0.5mm diameter PVDF membrane hydrophone. We present theoretical and experimental evaluations of V_E for the crossbeam geometry at frequencies within the transducers' bandwidth, and its application to tissue microstructure characterization.

Citation Download Citation

Navalgund A. H. K. Rao, Monica Barbu-McInnis, Maria Helguera, and Charles J. Daly "Diffraction-limited 3D cell volume derivation for scattering data analysis", Proc. SPIE 4687, Medical Imaging 2002: Ultrasonic Imaging and Signal Processing, (11 April 2002); https://doi.org/10.1117/12.462170

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