Application of high-pressure Raman spectroscopy to bone biomechanics

Michael D. Morris; Olivia de Carmejane; Angela Carden; M. Kathleen Davis; Lars Stixrude; Mary Tecklenburg; Rupak M. Rajachar; David H. Kohn

doi:10.1117/12.477940

22 July 2003 Application of high-pressure Raman spectroscopy to bone biomechanics

Michael D. Morris, Olivia de Carmejane, Angela Carden, M. Kathleen Davis, Lars Stixrude, Mary Tecklenburg, Rupak M. Rajachar, David H. Kohn

Author Affiliations +

Proceedings Volume 4958, Advanced Biomedical and Clinical Diagnostic Systems; (2003) https://doi.org/10.1117/12.477940
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

Compressive stress on bone, cartilage and other tissues accompanies normal activity. While the biomechanical properties of many tissues are reasonably well-understood at many levels of structure, surprisingly little is known at the ultrastructural and crystal lattice levels. We show how the use of diamond anvil cell Raman microspectroscopy enables a deeper understanding of the response of tissue to mechanical stress. We discuss the reversible responses of deproteinated and intact bone powders to hydrostatic pressure and compare these responses to those of a model compound, synthetic carbonated apatite.

Citation Download Citation

Michael D. Morris, Olivia de Carmejane, Angela Carden, M. Kathleen Davis, Lars Stixrude, Mary Tecklenburg, Rupak M. Rajachar, and David H. Kohn "Application of high-pressure Raman spectroscopy to bone biomechanics", Proc. SPIE 4958, Advanced Biomedical and Clinical Diagnostic Systems, (22 July 2003); https://doi.org/10.1117/12.477940

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available