Feasibility assessment of optical noninvasive total hemoglobin measurement

Martin P. Debreczeny; Paul Stetson; Clark Baker

doi:10.1117/12.479180

23 July 2003 Feasibility assessment of optical noninvasive total hemoglobin measurement

Martin P. Debreczeny, Paul Stetson, Clark Baker

Proceedings Volume 4965, Optical Diagnostics and Sensing in Biomedicine III; (2003) https://doi.org/10.1117/12.479180
Event: Biomedical Optics, 2003, San Jose, CA, United States

Abstract

A series of experiments were performed to assess the feasibility of measuring total hemoglobin (Hb_T) non-invasively using light in the visible to near infrared (NIR) range. The experiments included spectroscopic measurements of both in vitro isolated tissue components and in vivo human tissue (73 subjects) in a clinical setting. Several different methods of estimating Hb_T, all by optical non-invasive means, were tested and compared for accuracy relative to standard invasive methods. By combining time-resolved optical absorbances at 3 wavelengths, 750, 965, and 1320 nm, in a fashion that is highly analogous to pulse oximetry, Hb_T was predicted with a standard error of 1.1 g/dL.

Citation Download Citation

Martin P. Debreczeny, Paul Stetson, and Clark Baker "Feasibility assessment of optical noninvasive total hemoglobin measurement", Proc. SPIE 4965, Optical Diagnostics and Sensing in Biomedicine III, (23 July 2003); https://doi.org/10.1117/12.479180

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