Integrating NanoOptical Biosensors into Nucleic Acid Testing Devices

Qi-Huo Wei; Jian Gu; Chia-Fu Chou; Frederic Zenhausern

doi:10.1117/12.537799

25 June 2004 Integrating nano-optical biosensors into nucleic acid testing devices

Qi-Huo Wei, Jian Gu, Chia-Fu Chou, Frederic Zenhausern

Proceedings Volume 5363, Emerging Optoelectronic Applications; (2004) https://doi.org/10.1117/12.537799
Event: Integrated Optoelectronic Devices 2004, 2004, San Jose, CA, United States

Abstract

Nano optical biosensors employ the interaction between biomolecules and light confined in nanometer scale structures to report the bio-recognition events. This small scale sensing area/volume can ensure that small amount of biorecognition events could be detected. The exceptional sensitivity and high spatial density of nano optical biosensors make them unique in practical applications in nucleic acid detection. Lab-on-a-Chip systems provide the capabilities of separation, cell lysing, polymerase chain reaction (PCR), allowing finishing bio agent detection processes on a chip. In this paper, we present our recent efforts on integrating some novel nanooptical biosensors into Lab-on-a-Chip systems and some preliminary test results.

Citation Download Citation

Qi-Huo Wei, Jian Gu, Chia-Fu Chou, and Frederic Zenhausern "Integrating nano-optical biosensors into nucleic acid testing devices", Proc. SPIE 5363, Emerging Optoelectronic Applications, (25 June 2004); https://doi.org/10.1117/12.537799

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