Artificial bilayer lipid membranes (BLMs) on-chip for single molecule sensing

Mairi E. Sandison; Daniele Malleo; David Holmes; Richard Berry; Hywel Morgan

doi:10.1117/12.608645

28 June 2005 Artificial bilayer lipid membranes (BLMs) on-chip for single molecule sensing

Mairi E. Sandison, Daniele Malleo, David Holmes, Richard Berry, Hywel Morgan

Proceedings Volume 5838, Nanotechnology II; (2005) https://doi.org/10.1117/12.608645
Event: Microtechnologies for the New Millennium 2005, 2005, Sevilla, Spain

Abstract

A polymer microfluidic device for the formation of artificial bilayer lipid membranes (BLMs) on-chip is described. The device is fabricated from thin, transparent films of poly(methyl methacrylate), allowing for optical monitoring of the BLM. In addition, detection of single fluorescently-labeled lipid molecules using conventional epifluorescence microscopy is described.

Citation Download Citation

Mairi E. Sandison, Daniele Malleo, David Holmes, Richard Berry, and Hywel Morgan "Artificial bilayer lipid membranes (BLMs) on-chip for single molecule sensing", Proc. SPIE 5838, Nanotechnology II, (28 June 2005); https://doi.org/10.1117/12.608645

ACCESS THE FULL ARTICLE

INSTITUTIONAL
Select your institution to access the SPIE Digital Library.

SELECT YOUR INSTITUTION

PERSONAL
Sign in with your SPIE account to access your personal subscriptions or to use specific features such as save to my library, sign up for alerts, save searches, etc.

PERSONAL SIGN IN

No SPIE Account? Create one

PURCHASE THIS CONTENT

SUBSCRIBE TO DIGITAL LIBRARY

50 downloads per 1-year subscription

Members: $195

Non-members: $335 ADD TO CART

25 downloads per 1 - year subscription

Members: $145

Non-members: $250 ADD TO CART

PURCHASE SINGLE ARTICLE

Includes PDF, HTML & Video, when available