A new contrastive method for measuring surface tension of the human cornea in vivo

Jianguo Ma; Xueyong Zhang

doi:10.1117/12.716322

13 October 2006 A new contrastive method for measuring surface tension of the human cornea in vivo

Jianguo Ma, Xueyong Zhang

Proceedings Volume 6280, Third International Symposium on Precision Mechanical Measurements; 62803N (2006) https://doi.org/10.1117/12.716322
Event: Third International Symposium on Precision Mechanical Measurements, 2006, Urumqi, China

Abstract

A new contrastive method to measure the surface tension of the human cornea in vivo is introduced. Analyzing pressure-volume relationships and conditions of force equilibriums during the indention and applanation tonometry, the relationship of the intraocular pressure value and the change of the intraocular volume measured in the applanation tonometry as a function of the difference in the intraocular pressure between the indention and applanation tonometer readings, which was derived, the coefficient of surface tension for the human cornea was further obtained using this relationship and the difference also relative to the coefficient was considered to be the contribution of the surface tension of the human cornea. Laboratory experiments were carried out on a stimulated eyeball connected to a hydraulic manometer to accomplish the intraocular pressure at different levels. The stimulated eyeball at a chosen intraocular pressure level was measured with Schiotz indention tonometry, followed, according to the same change of intraocular volume, by Ma applanation tonometry. Preliminary experimental results showed the coefficient of the surface tension for the cornea agreed with the value calculated. This contrastive method may therefore be used to determine the coefficient of the surface tension for the human cornea and to estimate the surface tension of the human cornea in vivo. Further study including clinical trials and application is required to evaluate the usefulness and accuracy of this method.

Citation Download Citation

Jianguo Ma and Xueyong Zhang "A new contrastive method for measuring surface tension of the human cornea in vivo", Proc. SPIE 6280, Third International Symposium on Precision Mechanical Measurements, 62803N (13 October 2006); https://doi.org/10.1117/12.716322

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KEYWORDS

Cornea

In vivo imaging

Virtual colonoscopy

Clinical trials

Eye

Mechanics

Laser vision correction

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