We studied ischemia and reperfusion in island groin flaps for nine Charles River rats.
When the artery and/or vein are clamped, the oxygen saturation of hemoglobin
(StO2) measured by an infra-red spectroscopic device (ViOptix, Inc., Fremont, CA)
dropped significantly. The drop in arterial occlusion was usually faster than that in
venous occlusion. When the clamp was released after more than 1 hour of vessel
occlusion, the StO2 value came back, typically not to the pre-occlusive level but only
about half of it.
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